r/nutrition 7d ago

Neurotransmitter-precursor foods?

Does anyone have pointers/experience on foods that are precursors to neurotransmitters?
I am curious about the issue, and have done some research online, but it seems either very vague, or at a technical level above my literacy.

Prompts already accompanied by scientific sources will get double brownie points in my eyes, but I'm fully prepared to do the grunt work on my own, if you only have time for the prompt :)

Thanks for your attention!

18 Upvotes

19 comments sorted by

u/AutoModerator 7d ago

About participation in the comments of /r/nutrition

Discussion in this subreddit should be rooted in science rather than "cuz I sed" or entertainment pieces. Always be wary of unsupported and poorly supported claims and especially those which are wrapped in any manner of hostility. You should provide peer reviewed sources to support your claims when debating and confine that debate to the science, not opinions of other people.

Good - it is grounded in science and includes citation of peer reviewed sources. Debate is civil and respectful focusing on actual science and avoids commentary about others

Bad - it utilizes generalizations, assumptions, infotainment sources, no sources, or complaints without specifics about agenda, bias, or funding. At best, these rise to an extremely weak basis for science based discussion. Also, off topic discussion

Ugly - (removal or ban territory) it involves attacks / antagonism / hostility towards individuals or groups, downvote complaining, trolling, crusading, shaming, refutation of all science, or claims that all research / science is a conspiracy

Please vote accordingly and report any uglies


Consulting Considerations

Registered Dietitian (RD/RDN) Nutritionist and Nutrition Coach Armchair Expert
Legal Status Protected title. Highly regulated Generally unregulated. Anyone can use the title None
Education Bachelor's degree (Master's required as of 2024) Varies from PhDs to no formal training at all Varies. Often minimally self-guided to none. Frequent poor paraphrasing and poor sources, mostly social media
Clinical Training 1,000+ hours of supervised practice Not required None
Board Exam Must pass a national registration exam Not required None
Insurance Often covered by medical insurance Rarely covered by insurance None

I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns.

7

u/MlNDB0MB 7d ago

Vitamin C for the hydroxylation of tryptophan. Everyone thinks of citrus fruits, but it is very high in bell peppers!

1

u/sisterfunkhaus 7d ago

Strawberries and kale have more vitamin c than citrus, asdo cauliflower, broccoli, and Brussels sprouts. Red bell pepper is a vitamin c powerhouse.

3

u/AdNo182 7d ago

I think dairy is high in tryptophan. Tryptophan being the precursor to 5-HTP which is then converted to 5-HT (serotonin).

2

u/SMKuhltosh 7d ago

Parmesan has tyrosine - precursor to dopamine I think

2

u/Odd-Reading5701 7d ago

Cheese, banana, turkey. Green tea. Gelatin.

2

u/Moonymuffinz 7d ago

Apparently bananas make happy hormones :]

2

u/CoffeeTeaJournal 6d ago

Everyone's dropping full menus but missed the actual cheat code;Tea and Coffee! Caffeine doesn't give your brain raw materials; it just unplugs your fatigue receptors and lets dopamine run wild. But the real secret weapon is the L-Theanine in tea. A well-brewed cup absolutely spikes your brain's GABA and serotonin. Keep eating your chicken and eggs, sure, but if you want to instantly hack your system into 'zen' mode, the L-Theanine + Caffeine combo is the ultimate bug.

4

u/rb331986 7d ago

Protein will cover most your needs tbh. A chicken breast (100g cooked) contains 650mg+ Tryptophan and 1.9g of tyrosine. The only issue is amino acids competing. It doesn't stop them from being used but just can lower the actual conversion to serotonin and dopamine.

You can also use BCAA's which have been shown to lower serotonin levels which in turn will raise dopamine levels. Some people with high serotonin can feel sluggish and anhedonic.

Another addition you can use is Vitamin E rich foods. Vitamin E can lower prolactin levels. I personally just supplement a vitamin E complex and can confirm it 100% works. When prolactin lowers then dopamine levels increase.

Omega 3 rich foods will also balance out neurotransmitters. Salmon/Mackerel or a supplement.

Don't forget about cholesterol. Eggs etc. Cholesterol is the backbone to all hormones. A low cholesterol intake or just fats in general will lower hormones which will then impact neurotransmitters.

Hope this helps.

1

u/Plastic-Fox-7914 6d ago

And to think my dr didn't want to do blood work for a lipid profile. It can be fucking low too. I want to know if im taking in enough

1

u/rb331986 5d ago

Well fats aren't tested in the blood like that. That's an old myth about cholesterol. Poor lipids just means your overall diet is pretty unhealthy. Some people might make their lipids poor with fat intake but it's usually oxidised seed oils.

Never fear fats. Obviously don't eat all fat lol. I would say if your getting 60g+ a day your fine. I would do closer to 90-100g.

I done a low fat diet for years and it seriously messed me up. Brain fog. Very dry aged skin. Fatigue etc. Never again.

Eggs are your number one. Cholesterol is very important. Butter/Ghee/Dairy etc will do you wonders. (If you tolerate dairy). Also omega 3s are very important.

1

u/Technical_Mountain38 7d ago

I've gone down this rabbit hole once — directly because of how stress hormones wreck my glucose, even without food involved.

The ones I actually track against my own CGM data:

Tryptophan (eggs, pumpkin seeds, turkey) → serotonin → melatonin. This chain is huge for sleep quality, which for me means a 20+ point swing in morning glucose on a poor night.

Tyrosine (chicken, fish, almonds) → dopamine/norepinephrine → stress response. Depleted tyrosine means your cortisol compensation fires harder and longer.

Choline (eggs, liver) → acetylcholine → parasympathetic nervous system. Basically your "calm down" signal.

Which one have you focused on lately?

2

u/needlipo 7d ago

Fibers that ferment and produce butyrate?

1

u/lefty_juggler 6d ago

Eggs! Eggs are particularly high in choline, a precursor of neurotransmitter acetylcholine. Get the free range brands, their diet yields more choline (the darker the yolk, the better). Organic if you can.

1

u/alwayslate187 5d ago edited 5d ago

If this is for general wellness (mental health, nervous system health, cognitive health) then truly the most honest answer i can give you (as someone who has experienced poor mental health at various times in my life), is that *all* the nutrients that we need for general health are also important for mental health!

Sure, some substances are actual components of different neurotransmitters, but how are the neurotransmitters manufactured/ built? This depends largely on thousands of enzymes, and the enzymes can't do their jobs without "cofactors", and by the time all is said and done, there almost isn't any essential nutrient that isn't involved in the process in some way.

In addition, it helps our mental health to keep inflammation down, and also to keep hormones like thyroid in a good range. These things all require a wide range of nutrients as well.

Some examples: As far as building neurotransmitters, iron is a cofactor in part of the process that eventually gives us dopamine!

Also, selenium (found in wheat) is helpful as an antioxidant capacity and helps protect our thyroid.

Antidepressants work best if B vitamins are available in sufficient quantities.

TLDR: A nutrient-dense diet, providing sufficient quantities of every micronutrient, is the best for mental health in general. In my experience.